Daycare wise this completely upended my program. I structured my program to do a lot of offsite activities & learning opportunities. Library trips, zoo trips, grocery to talk about nutrition & trying new foods, farm or pet store for feed for the animals, etc. We were out and about 2-3 times a week. Even after things lift I think it will be a while before I could go back to that. So 14 years of teaching style and one of the big things that made my program unique are done. Not to mention one of my best marketing tools. That and my MIL not leaving the house at least once a day to give me a break from her.
Personally it's the basics- being able to go see family, quick trip to the store, and knowing what this is doing to so many of my friends. People who've built business are watching it put in peril. And planning things- ballgames, weekend or day trips, events both business and pleasure are toast right now. Understandable but still frustrating.