I agree with PPs who suggest having a trusted family member/neighbor/friend if you can. Finding a sub that you trust with your business and these little people's lives is very nerve-wracking.
If you don't aleady know someone that you trust, does your city have a facebook page for moms or just community members? What about talking with your current families...maybe they know someone. Does your wife do field trips with the kids-I always met a lot of moms at library storytimes...perhaps she'd develop some friendships there.
I finally have a sub this year (a very good friend of mine) to cover my appts and maternity leave. I'm keeping her next year but really have to give her at least 1 full day a week of work in order to keep her here. After that, she said she'll be ready for more work (she's currently a stay at home mom) and I won't be able to give her more days, so I'm going to lose her.
